Resources for Nurses
Quality of life measurement questionnaires :
Definition: The FACT-P is a multidimensional, self-report QoL instrument specifically designed for use with prostate
cancer patients (1, 2, 3). It consists of 27 core items which assess patient function in four domains: Physical, Social/
Family, Emotional, and Functional well-being, which is further supplemented by 12 site specific items to assess for
prostate related symptoms. Each item is rated on a 0 to 4 Likert type scale, and then combined to produce subscale
scores for each domain, as well as a global QoL score. Higher scores represent better QoL. Version 4 retains most items
from Version 3, however some items have been reworded and adjustments will have to be made in comparing scores
ECOG: Performance status:
Definition: The ECOG performance status is a scale used to assess how a patient's disease is progressing, assess
how the disease affects the daily living abilities of the patient, and determine appropriate treatment and prognosis.
Figure 1: Management of castration-resistant prostate cancer (CRPC). PSADT : prostate-specific antigen doubling time. mCRPC: metastatic CRPC.
In the presence of bone metastases:
Denosumab or Zoledronic Acid are recommended to reduce the risk of skeletal complications
Palliative radiation therapy should be considered in patients with pain
Management of comorbidities in CRPC: